Doxorubicin hydrochloride liposome and albumin-bound paclitaxel in cancer: a nanotechnology perspective
نویسندگان
چکیده
منابع مشابه
Comparing adverse effects of docetaxel-doxorubicin and paclitaxel-doxorubicin regimens in breast cancer patients
Introduction: Taxanes have emerged as one of the most active agents in the treatment of patients with breast cancer. Nevertheless, questions remain with regard to their toxicity profiles. This study aimed to compare prevalence and severity of adverse effects of two chemotherapy regimens including taxanes (docetaxel or paclitaxel) in breast cancer patients. Materials and Methods: Fifty patients ...
متن کاملAlbumin-Bound Paclitaxel in the Treatment of Metastatic Breast Cancer
The taxanes, paclitaxel and docetaxel, are an important class of antineoplastic agents with relevant clinical activity in both early and advanced breast cancer. Nanoparticle albumin-bound paclitaxel (Abraxane®) is a 130–nm particle cremophor-free formulation of paclitaxel. Exploiting endogenous albumin pathways and avoiding solvent-based toxicities, nab-paclitaxel allows higher intratumor conce...
متن کاملA Retrospective Study of Efficacy and Safety of Albumin-Bound Paclitaxel in Metastatic Breast Cancer
Background Nab-paclitaxel is a novel nanoparticle, albumin-bound, solvent-free, taxane-based chemotherapy approved for the treatment of metastatic breast cancer (MBC). This study reports clinical benefit and toxicities experienced by women with MBC treated with nab-paclitaxel. Methods Women with MBC treated with single-agent nab-paclitaxel between January 2012 and March 2014 were included in ...
متن کاملSuperior Therapeutic Efficacy of Nanoparticle Albumin Bound Paclitaxel Over Cremophor-Bound Paclitaxel in Experimental Esophageal Adenocarcinoma
Esophageal adenocarcinoma (EAC) is the fastest growing cancer in the western world and the overall 5 year survival rate of EAC is below 20%. Most patients with EAC present with locally advanced or widespread metastatic disease, where current treatment is largely ineffective. Therefore, new therapeutic approaches are urgently needed. Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) is a no...
متن کاملNanoparticle albumin-bound paclitaxel as neoadjuvant chemotherapy of breast cancer: a systematic review and meta-analysis
BACKGROUND The value of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) in neoadjuvant systemic therapy for breast cancer remains uncertain. METHODS Both electronic databases and proceedings of oncologic meetings were included in systematic literature search. Pooled rates of pathological complete response (pCR), odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using...
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ژورنال
عنوان ژورنال: The Applied Biology & Chemistry Journal
سال: 2021
ISSN: 2582-8789
DOI: 10.52679/tabcj.2021.0010